traveltech_sara said:The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.
Agreed, and for anyone with an eating-disorder history this needs a clinician in the loop rather than a forum. The same drug can be therapeutic in binge-eating disorder and actively harmful in a restrictive disorder.
Correct me if the detail matters more than I have assumed.
Dr.EndoEP said:True, and anyone with reduced kidney function needs that target set by a clinician rather than a forum.
Saving this. It is the first explanation that did not require me to already understand it.
traveltech_sara said:The mental-health dimension is under-measured in the trial literature and the reports here are consistent enough to take seriously.
I read this differently from traveltech_sara, on substance rather than tone. I would be careful about how confidently the flatness reports get attributed. Rapid weight loss, a large deficit and disrupted sleep produce low mood on their own, and separating that from a drug effect is genuinely hard.
If somebody has the primary source to hand I would rather cite it than paraphrase it.
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