julia.endo said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
There is a second half to this that has not been said yet. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.
Ask again with the specifics and you will get a better answer than this one.
Following on from julia.endo — and this may be the naive question:
Did your prescriber agree with that reading, and if not what was their objection?
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Browse GL BiochemDr.AddMedPHL said:If you are going to change something, change one thing and give it long enough to express itself.
Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.
Happy to go further on any of that.
Dr.AddMedPHL said:If you are going to change something, change one thing and give it long enough to express itself.
That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.