DeniseRN_TPA said:The mechanism and the magnitude are separate questions.
Adding the part of the answer the thread has not reached. SURMOUNT-1 landed around 20.9% mean weight loss at 15mg over 72 weeks, against roughly 15% for semaglutide 2.4mg in STEP 1. Different trials, different populations, so the comparison is indicative rather than decisive — but SURPASS-2 was a genuine head-to-head and it pointed the same way.
One concrete data point for the thread. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.
A narrower follow-up, since the general answer is now clear:
Did your prescriber agree with that reading, and if not what was their objection?
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Browse GL BiochemHPLC_Greg said:Worth stating the units and the reference range whenever you post a number here.
I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.
Happy to go further on any of that.
HPLC_Greg said:Worth stating the units and the reference range whenever you post a number here.
That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.