PeptideChemSF said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.
Correct me if the detail matters more than I have assumed.
Found this through search years later and it is still the best discussion of the question, so adding one thing. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.
Clinical perspective, offered as context rather than as advice. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.
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View Resultsjim_asheville said:It is worth asking what the claim would look like if it were false.
Mine went the same way, slower.
jim_asheville said:It is worth asking what the claim would look like if it were false.
Coming at jim_asheville’s question from a different direction. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.