Triglycerides dropped by half, HDL barely moved, and my calculated LDL is almost exactly where it started, which is not the outcome I had been promised.
The question I want answered is whether an unchanged LDL-C alongside a large triglyceride fall is a good result or a bad one, because ApoB and LDL-C seem to be telling different stories.
Not looking for reassurance. Looking for the part I have got wrong.
ricardo_MIA said:Triglycerides dropped by half, HDL barely moved, and my calculated LDL is almost exactly where it started, which is not the outcome I had been…
Tracking labs for the lipid panel — here's the panel I get every 3 months and why:
- CMP: glucose, electrolytes, kidney function, liver enzymes
- Lipid panel: total cholesterol, LDL, HDL, triglycerides
- A1C: 3-month glucose average
- hsCRP: inflammatory marker
- CBC: blood counts, anemia screening
- B12, folate, iron: nutritional deficiency screening
- TSH, free T4: thyroid monitoring
- Lipase: pancreatic safety check
Total cost with insurance: about $25 copay. Without insurance, request cash-pay pricing from Quest/Labcorp — usually $160.
Dr.RaviCardio said:Tracking labs for the lipid panel — here's the panel I get every 3 months and why: CMP: glucose, electrolytes, kidney function, liver enzymes Lipid…
Omega-3 index improvement on the lipid panel: often overlooked but my omega-3 index went from 3.5% to 7.5% over 8 months. I supplemented with 2g EPA+DHA daily.
This matters because omega-3s are anti-inflammatory and cardioprotective, complementing the GLP-1 benefits. Target omega-3 index is >8%. Combined with the triglyceride reduction from the medication, my lipid profile is the best it's been in decades.
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View Resultsricardo_MIA said:Triglycerides dropped by half, HDL barely moved, and my calculated LDL is almost exactly where it started, which is not the outcome I had been…
Same experience, arrived at from the opposite direction.
Adding the clinical framing, because it changes how the question reads.
Before/after bloodwork compilation for the lipid panel — everything in one place for those who want comprehensive data:
| Category | Marker | Before | After 12mo | Change |
|---|---|---|---|---|
| Metabolic | A1C | 7.4% | 5.4% | ⬇️ 1.6% |
| Metabolic | Fasting Glucose | 132 | 89 | ⬇️ 27 |
| Lipids | LDL | 150 | 94 | ⬇️ 52 |
| Lipids | Triglycerides | 252 | 122 | ⬇️ 102 |
| Inflammation | hsCRP | 5.5 | 1.0 | ⬇️ 6.0 |
Every single metabolic marker improved. This is why I'm a believer in this therapy.