Dr.GutHealth said:The pharmacokinetics explain nearly every practical question asked here.
Agreed, and the adaptation point cuts both ways: tachyphylaxis to gastric emptying is why tolerability improves, and it is also why people who were relying on physical fullness feel the effect fade while the appetite effect is still working.
nick_newbie said:True, though the ladder is longer and that is not a neutral detail — six dose steps means six opportunities to stall on the way up, and plenty of…
Bookmarking. The distinction being drawn above is the one nobody else makes. Printing the relevant bit and taking it with me.
Dr.GutHealth said:The pharmacokinetics explain nearly every practical question asked here.
Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.
Correct me if the detail matters more than I have assumed.
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View ResultsAdding the numbers, since they settle part of this. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.
Moderator note: the sourcing question belongs in the vendor section and has been split out. Report rather than reply if it drifts again.