jim_asheville said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.
sarah.morrison said:True, though the ladder is longer and that is not a neutral detail — six dose steps means six opportunities to stall on the way up, and plenty of…
That reframing is the part I needed. Adding it to my notes with a link back to this thread.
jim_asheville said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Pushing back on jim_asheville here. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
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View ResultsAdding the numbers, since they settle part of this. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.
Happy to go further on any of that.