Dr.EndoIndy said:Propensity score matching studies and the trial evidence: when RCTs aren't available for a specific question, propensity score-matched observational…
That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.
alex_tucson said:Bayesian meta-analysis perspective on the trial evidence: traditional frequentist meta-analyses report point estimates and confidence intervals.
That reframing is the part I needed. Printing the relevant bit and taking it with me.
Dr.EndoIndy said:Propensity score matching studies and the trial evidence: when RCTs aren't available for a specific question, propensity score-matched observational…
Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.
Correct me if the detail matters more than I have assumed.
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View ResultsOne concrete data point for the thread. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.
That is the short version; the long version is somebody else's post.
Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Thread quality here is what the rules are for. Keep it up.