PeptideSynthNJ said:Freezing is the one to avoid, and freeze-thaw more so.
Storage best practices for compounded storage and cold:
- Unreconstituted lyophilized powder: refrigerate (36-46°F), good for 12+ months
- Reconstituted vials: refrigerate, use within 28 days
- Pre-filled pens: refrigerate until first use, then room temp OK for 28 days
- Never freeze reconstituted peptides — ice crystals damage the protein
- Protect from light — store in original box or wrap in foil
When in doubt, refrigerate. Temperature abuse is the #1 cause of reduced potency in compounded peptides.
One thing that is still open after NurseAsh_DET’s answer:
Did your prescriber agree with that reading, and if not what was their objection?
PharmacoVig_BOS said:Storage best practices for compounded storage and cold: Unreconstituted lyophilized powder: refrigerate (36-46°F), good for 12+ months Reconstituted…
Coming at PharmacoVig_BOS’s question from a different direction. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.
Sigma-Aldrich — Research-Grade Standards
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Shop Reference StandardsOP back with an update, since a thread like this is useless without one.
Update: the excursion was survivable and the vial was fine. I now keep a cheap fridge thermometer, which costs nothing and ends the argument.
LipidDoc_ATL said:It is worth asking what the claim would look like if it were false.
Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.