Dr.DermMIA said:Relative and absolute effects need reading together.
Agreed, and subgroup analyses deserve particular suspicion. With enough subgroups something is significant by chance, and pre-registered subgroups are a different animal from ones found afterwards.
EndoResFellow said:Worth adding that the tablet is taken daily, so a missed dose costs far less than a missed weekly injection.
This is exactly what I could not find anywhere else. I will report back once I have actually tried it.
Dr.DermMIA said:Relative and absolute effects need reading together.
Pushing back on Dr.DermMIA here. I would add the less popular caveat: these trial populations under-represented several groups, older adults and the highest BMI categories among them. The results probably generalise, and "probably" should be stated as an assumption rather than dropped.
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View ResultsOne concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.
Ask again with the specifics and you will get a better answer than this one.