The figures, for anyone assembling their own picture. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.
Ask again with the specifics and you will get a better answer than this one.
A narrower follow-up, since the general answer is now clear:
Whether the fasting requirement is as strict in practice as the label implies, and what people actually see when they get it wrong?
DoseLogDan said:If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.
Adding the part of the answer the thread has not reached. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
I would rather be corrected than agreed with, if it comes to it.
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Follow-up: moving the tablet to the moment I wake, before anything else, was the whole fix. The dose never changed.
anders_CPH said:The mechanism and the magnitude are separate questions.
No disagreement with anders_CPH. One condition attached. The absorption variability is real, but it partly averages out over weeks — the steady-state trough is less erratic than any single day would suggest. Where it bites is in the first fortnight, when people conclude the tablet does nothing.
That is the short version; the long version is somebody else's post.