sophie_paris said:The mechanism is more central than most summaries suggest.
That holds for the injectable. The oral formulation has different absorption behaviour and the dose numbers are not interchangeable, which is worth saying out loud because people quote them as if they were.
zoe_NC said:The mechanism that matters here is not stomach emptying, it is central.
This is exactly what I could not find anywhere else.
sophie_paris said:The mechanism is more central than most summaries suggest.
I read this differently from sophie_paris, on substance rather than tone. The trial means are being read too generously in this thread. STEP populations were selected, supported, and titrated by protocol, and the real-world curves are consistently a few points worse. That difference is not noise, it is what happens when you remove the study infrastructure.
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