roxy_nash said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.
RunnerRach said:Agreed, with a caveat about community reputation: it is a lagging indicator.
Saving this. It is the first explanation that did not require me to already understand it. Taking it to my next appointment.
roxy_nash said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
I read this differently from roxy_nash, on substance rather than tone. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.
Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsThe figures, for anyone assembling their own picture. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.