I split my weekly dose in half for six weeks to see whether it smoothed the first two days out, and the result was less impressive than I expected.
What would genuinely help is knowing what the pharmacokinetic argument against splitting a weekly dose actually is, since intuitively it should smooth the curve.
Practical detail welcome, however dull — the duller the better.
steph_laguna said:I split my weekly dose in half for six weeks to see whether it smoothed the first two days out, and the result was less impressive than I expected.
Dose splitting update on split dosing: instead of 2.4mg once weekly, I've been doing 1.2mg twice weekly (Mon/Thu) with my doctor's approval. The appetite suppression is more consistent and side effects are noticeably milder.
Not medical advice, just sharing what's worked for me. Discuss with your provider before trying this.
Dr.GastroMayo said:Dose splitting update on split dosing: instead of 2.4mg once weekly, I've been doing 1.2mg twice weekly (Mon/Thu) with my doctor's approval.
Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.
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Shop Reference Standardssteph_laguna said:I split my weekly dose in half for six weeks to see whether it smoothed the first two days out, and the result was less impressive than I expected.
This is my experience too, for whatever a second data point is worth.
Clinical perspective, offered as context rather than as advice. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.